CD43 antibody [MEM-59] (APC-Cy7)

Catalogue Number: GTX29088-15-GTX

Manufacturer:	GeneTex
Preservative:	15 mM Sodium azide
Molecular Weight:	40
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD43 , GALGP , GPL115 , LSN , SPN , sialophorin
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	MEM-59
Isotype:	IgG1
Immunogen:	Human T lymphocytes.
Application:	FC

Overview
Datasheets

Description

Description: This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

Additional Text

Gene Name

SPN

Uniprot ID

P16150

Gene ID

6693

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX29088-15 Datasheet

Price

£312.00

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Quantity
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