NAP2 antibody

Catalogue Number: GTX29554-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:14
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:pro-platelet basic protein , B-TG1 , Beta-TG , CTAP-III , CTAP3 , CTAPIII , CXCL7 , LA-PF4 , LDGF , MDGF , NAP-2 , PBP , SCYB7 , TC1 , TC2 , TGB , TGB1 , THBGB , THBGB1
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Highly pure (>98%) recombinant human NAP2 (human Neutrophil Activating Protein-2).
Application: ELISA, WB, NT, Inh

Description

Description: The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]

Additional Text

Uniprot ID

P02775

Gene ID

5473

Gene Name

PPBP

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

14

Application Notes

Neutralization:To yield one-half maximal inhibition [ND50] of the biological activity of hNAP-2 (50 ng/ml), a concentration of 1.75 - 3.0 µg/ml of this antibody is required. ELISA:To detect hNAP-2 by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hNAP-2. Western Blot:To detect hNAP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hNAP-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.