Rad51C antibody [2H11/6]

Catalogue Number: GTX30137-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:42
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:RAD51 paralog C , BROVCA3 , FANCO , R51H3 , RAD51L2
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 2H11/6
Isotype: IgG1
Immunogen: His-tagged human Rad51C, over-expressed in E. coli. [UniProt# O43502]
Application: FC, ICC, IF, IHC-P, IP, WB, MS

Description

Description: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq]

Additional Text

Gene ID

5889

Uniprot ID

O43502

Molecular Weight

42

Gene Name

RAD51C

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.

Application Notes

WB: 1:1000. FCM: 1 µg / 10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.