Catalogue Number: GTX30137-GTX
Manufacturer: | GeneTex |
Preservative: | 0.02% Sodium azide |
Physical state: | Liquid |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | RAD51 paralog C , BROVCA3 , FANCO , R51H3 , RAD51L2 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Mouse |
Clone: | 2H11/6 |
Isotype: | IgG1 |
Immunogen: | His-tagged human Rad51C, over-expressed in E. coli. [UniProt# O43502] |
Application: | FACS, ICC, IF, IHC-P, IP, WB, MS |
Description: This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq]
1 mg/ml
5889
O43502
42
RAD51C
Protein G purified
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
WB: 1:1000. FACS: 1 µg / 10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.