Mre11 antibody
Catalogue Number: GTX30294-GTX
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GTX30294 Image
GTX30294 Image
GTX30294 Image
GTX30294 Image
WB analysis of HeLa and MEF cell lysate using GTX30294 Mre11 antibody.
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WB analysis of HeLa cell lysate using GTX30294 Mre11 antibody.
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ICC/IF analysis of HeLa cells using GTX30294 Mre11 antibody. Green : primary antibody Red : Actin Blue : DAPI Dilution : 1:500 Fixation : 10% formalin Permibilization : 0.5% Triton-X100
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IHC-P analysis of human epidermis tissue cross section using GTX30294 Mre11 antibody.
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 81 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | MRE11 homolog, double strand break repair nuclease , ATLD , HNGS1 , MRE11A , MRE11B |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Full length human Mre11 protein. [UniProt# P49959] |
| Application: | FC, ICC, IF, IHC-P, IP, ChIP, WB, IHC-Fr |
Description
Description: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]
Additional Text
Gene ID
4361
Uniprot ID
P49959
Gene Name
MRE11
Purification
Unpurified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
81
Application Notes
WB: 1:5000. ICC/IF: 1:200. IHC-P: 1:10 - 1:500. IP: 3 ul. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX30294 Datasheet
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