Blimp1 antibody [3H2-E8]

Catalogue Number: GTX30605-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 3H2-E8
Isotype: IgG1
Immunogen: A fragment of mouse Blimp-1 corresponding to residues 199-409. [UniProt# Q60636]
Application: ELISA, ICC, IF, IHC-P, IP, ChIP, WB, IHC-Fr

Description

Description: Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus. It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.

Additional Text

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 1:1000. ICC/IF: 1:50 - 1:200. IHC-P: 1:200. ELISA: 1:100 - 1:2000. ChIP assay: 1µg antibody / 10 µg protein. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.