EP300 antibody [RW109]

Catalogue Number: GTX30619-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:264
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:E1A binding protein p300 , KAT3B , MKHK2 , RSTS2 , p300
Shipping Condition:Blue Ice
Unit(s): 200 ul
Host name: Mouse
Clone: RW109
Isotype: IgG1
Immunogen: Fusion protein containing residues 1572-2371 of human KAT3B/p300. [UniProt# Q0947]
Application: ICC, IF, IP, ChIP, WB

Description

Description: Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.

Additional Text

Gene ID

2033

Gene Name

EP300

Uniprot ID

Q09472

Molecular Weight

264

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:1000. ICC/IF: 1:100 - 1:200. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.