Catalogue Number: GTX30619-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.1% Sodium azide |
| Molecular Weight: | 264 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | E1A binding protein p300 , KAT3B , MKHK2 , RSTS2 , p300 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ul |
| Host name: | Mouse |
| Clone: | RW109 |
| Isotype: | IgG1 |
| Immunogen: | Fusion protein containing residues 1572-2371 of human KAT3B/p300. [UniProt# Q0947] |
| Application: | ICC, IF, IP, ChIP, WB |
Description: Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
2033
EP300
Q09472
264
Unpurified
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
WB: 1:1000. ICC/IF: 1:100 - 1:200. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.