ATP7b antibody

Catalogue Number: GTX30639-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:157
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:ATPase copper transporting beta , PWD , WC1 , WD , WND
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide made to an internal sequence near the N-terminus of human ATP7b. [UniProt# P35670]
Application: ICC, IF, IHC-P, IP, WB, IHC, PLA

Description

Description: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq]

Additional Text

Gene Name

ATP7B

Uniprot ID

P35670

Gene ID

540

Purification

Affinity Purified

Molecular Weight

157

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 1:1000. ICC/IF: 2 - 10 µg/ml. IHC-P: 1:100 - 1:500. IHC: 1:100 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.