53BP1 antibody

Catalogue Number: GTX30658-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:214
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:tumor protein p53 binding protein 1 , 53BP1 , TDRD30 , p202 , p53BP1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A synthetic peptide corresponding to a portion of human 53BP1 encoded in exon 11, 12 and 19 [UniProt# Q12888]. This antibody is a cocktail hybrid of NB100-304 and NB100-305.
Application: ICC, IF, IHC-P, IP, WB, PLA

Description

Description: May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.

Additional Text

Gene Name

TP53BP1

Uniprot ID

Q12888

Gene ID

7158

Purification

Affinity Purified

Molecular Weight

214

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 1:1000 - 1:10000. ICC/IF: 1:100 - 1:1000. IHC-P: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.