Serotonin Transporter antibody, Internal

Catalogue Number: GTX31103-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:70
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:solute carrier family 6 member 4 , 5-HTT , 5-HTTLPR , 5HTT , HTT , OCD1 , SERT , SERT1 , hSERT
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Goat
Clone:
Isotype: IgG
Immunogen: Peptide with sequence C-LHQGERETWGK, from the internal region of the protein sequence according to NP_001036.1.
Application: ELISA, ICC, IF, WB

Description

Description: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

SLC6A4

Uniprot ID

P31645

Gene ID

6532

Concentration

0.5 mg/ml

Purification

Ammonium Sulfate Precipitated; Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

70

Application Notes

WB: 1-3 µg/mL. ICC/IF: 10 µg/ml/ml. ELISA: ≤1:32000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.