IL6 antibody
Catalogue Number: GTX31178-GTX
GTX31178 Image
GTX31178 Image
IHC analysis of colchicine injected mouse brain (cingulate cortex) tissue using IL6 antibody at a concentration of 0.5 µg/ml. This was followed by a peroxidase conjugated secondary antibody and then a fluorescein Tyramide Signal Amplification (TSA) reagent.
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 24 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | interleukin 6 , IL-6 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant Murine IL-6 |
| Application: | ELISA, WB, IHC-Fr, NT, Inh |
Description
Description: This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
Additional Text
Gene Name
IL6
Gene ID
16193
Molecular Weight
24
Uniprot ID
P08505
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
We recommend the following starting dilutions: For WB: Use at a concentration of 0.1-0.2 µg/ml. For ELISA: Use at a concentration of 0.5 - 2.0 µg/ml. For IHC-Fr: Use at a concentration of 0.5 µg/ml. For Neutralization: one-half maximal inhibition [ND50] of the biological activity of Mouse IL-6 (3 pg/ml), a concentration of 0.24-0.36 µg/ml of this antibody is required. Optimal dilutions should be determined experimentally by the end user.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX31178 Datasheet
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