TNF Receptor II antibody

Catalogue Number: GTX31250-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Molecular Weight:	48
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	TNF receptor superfamily member 1B , CD120b , TBPII , TNF-R-II , TNF-R75 , TNFBR , TNFR1B , TNFR2 , TNFR80 , p75 , p75TNFR
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Recombinant human TNF Receptor II.
Application:	ELISA, ICC, IF, WB, FA

Overview
Datasheets

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]

Additional Text

Uniprot ID

P20333

Gene Name

TNFRSF1B

Gene ID

7133

Purification

Affinity Purified

Molecular Weight

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 0.1-0.2µg/ml. ICC/IF: 3µg/ml. ELISA: 0.5-2µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX31250 Datasheet

Price

£386.00

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Quantity
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