TLR3 blocking peptide
Catalogue Number: GTX31291-PEP-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Physical state: | Liquid |
| Type: | Blocking Peptides |
| Alias: | Toll Like Receptor 3 , Cd283 , Iiae2 , Tlr3 |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
| Application: | NT, Inh |
Description
Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 200
Additional Text
Gene Name
TLR3
Gene ID
7098
Concentration
200 ug/ml
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Short Description
TLR3 peptide is used for blocking the activity of TLR3 antibody (catalog number GTX31291).
Storage Note
Store as concentrated solution. Aliquot and store at -20C or below. Avoid freeze-thaw cycles.
GTX31291-PEP Datasheet
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