CBL blocking peptide
Catalogue Number: GTX31301-PEP-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Physical state: | Liquid |
| Type: | Blocking Peptides |
| Alias: | Cbl Proto-Oncogene , C-Cbl , Cbl2 , Fra11B , Nsll , Rnf55 , Cbl |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
| Application: | NT, Inh |
Description
Description: This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Mar 2012]
Additional Text
Gene Name
CBL
Gene ID
867
Concentration
200 ug/ml
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Short Description
CBL peptide is used for blocking the activity of CBL antibody (catalog number GTX31301).
Storage Note
Store as concentrated solution. Aliquot and store at -20C or below. Avoid freeze-thaw cycles.
GTX31301-PEP Datasheet
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