MDA5 blocking peptide

Catalogue Number: GTX31305-PEP-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Physical state:Liquid
Type:Blocking Peptides
Alias:Interferon Induced With Helicase C Domain 1 , Ags7 , Hlcd , Iddm19 , Mda-5 , Mda5 , Rlr-2 , Sgmrt1 , Ifih1
Shipping Condition:Dry Ice
Unit(s): 50 ug
Application: NT, Inh

Description

Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012]

Additional Text

Gene ID

64135

Gene Name

IFIH1

Concentration

200 ug/ml

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

MDA5 peptide is used for blocking the activity of MDA5 antibody (catalog number GTX31305).

Storage Note

Store as concentrated solution. Aliquot and store at -20C or below. Avoid freeze-thaw cycles.