DYRK1A blocking peptide
Catalogue Number: GTX31433-PEP-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Physical state: | Liquid |
| Type: | Blocking Peptides |
| Alias: | Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A , Dyrk , Dyrk1 , Hp86 , Mnb , Mnbh , Mrd7 , Dyrk1A |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
| Application: | NT, Inh |
Description
Description: This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008]
Additional Text
Gene ID
1859
Gene Name
Dyrk1a
Concentration
200 ug/ml
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Short Description
DYRK1A peptide is used for blocking the activity of DYRK1A antibody (catalog number GTX31433).
Storage Note
Store as concentrated solution. Aliquot and store at -20C or below. Avoid freeze-thaw cycles.
GTX31433-PEP Datasheet
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