Histone H2A.Z (Acetyl Lys4) antibody [RM221]

Catalogue Number: GTX33591-GTX

Manufacturer:GeneTex
Preservative:0.09% Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:H2A histone family member Z,H2A.Z1,H2A.z,H2A/z,H2AFZ,H2AZ,Histone H2A.Z,H2A.Z variant histone 1
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone: RM221
Isotype: IgG
Immunogen: An acetyl-peptide corresponding to Acetyl-Histone H2A.Z (Lys4).
Application: ELISA, ICC, IF, WB

Description

Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

3015

Uniprot ID

P0C0S5

Modification

Acetylated, Lys4

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

14

Gene Name

H2AZ1

Application Notes

WB: 0.5 µg/mL - 2 µg/mL. ICC/IF: 1 µg/mL - 2 µg/mL. ELISA: 0.2 µg/mL - 1 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.