DR5 antibody [HS201] (Azide free)

Catalogue Number: GTX33945-GTX

Manufacturer:	GeneTex
Preservative:	Azide free\|no preservative\|No preservative
Molecular Weight:	48
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	TNF receptor superfamily member 10b , CD262 , DR5 , KILLER , KILLER/DR5 , TRAIL-R2 , TRAILR2 , TRICK2 , TRICK2A , TRICK2B , TRICKB , ZTNFR9
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	HS201
Isotype:	IgG1
Immunogen:	Recombinant human TRAIL-R2 (DR5).
Application:	FC, ICC, IF, IP, NT, Inh

Overview
Datasheets

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

Additional Text

Gene Name

TNFRSF10B

Uniprot ID

O14763

Gene ID

8795

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX33945 Datasheet

Price

£488.00

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