Arginase 1 antibody [ARG1/1126]

Catalogue Number: GTX34416-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:35
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:ARG1 , arginase 1 , Arginase 1 , Liver Arginase , Arginase I
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: ARG1/1126
Isotype: IgG3
Immunogen: Recombinant fragment (around aa11-97) of human ARG1 protein (exact sequence is proprietary)
Application: IHC-P, PA

Description

Description: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Additional Text

Gene Name

ARG1

Gene ID

383

Uniprot ID

P05089

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

IHC-P: 2-4µg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.