BCL6 antibody [BCL6/1527]
Catalogue Number: GTX34434-GTX
GTX34434 Image
GTX34434 Image
GTX34434 Image
GTX34434 Image
GTX34434 Image
IHC-P analysis of human tonsil tissue using GTX34434 BCL6 antibody [BCL6/1527].
GTX34434 Image
IHC-P analysis of human follicular lymphoma tissue using GTX34434 BCL6 antibody [BCL6/1527].
GTX34434 Image
IHC-P analysis of human Hodgkin's lymphoma tissue using GTX34434 BCL6 antibody [BCL6/1527].
GTX34434 Image
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 79 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | BCL5 , BCL6 , BCL6A , Bcell CLL/lymphoma 6 , LAZ3 , ZBTB27 , ZNF51 , BCL6 transcription repressor |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | BCL6/1527 |
| Isotype: | IgG1 |
| Immunogen: | Recombinant human bcl-6 protein fragment (around aa256-389) (Exact sequence is proprietary) |
| Application: | IHC-P, PA |
Description
Description: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Additional Text
Gene ID
604
Gene Name
BCL6
Uniprot ID
P41182
Purification
Protein A/G Purified
Concentration
0.2 mg/ml
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
IHC-P: 1-2µg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX34434 Datasheet
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