CD11c antibody [ITGAX/1243]

Catalogue Number: GTX34456-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:128
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD11C , ITGAX , SLEB6 , integrin subunit alpha X , CD11c , Integrin alpha X
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: ITGAX/1243
Isotype: IgG2b
Immunogen: Recombinant fragment (aa 637-827) of human ITGAX protein (exact sequence is proprietary)
Application: ELISA, PA

Description

Description: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Additional Text

Gene Name

ITGAX

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Gene ID

3687

Uniprot ID

P20702

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

ELISA: 2-4µg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.