CD27 antibody [LPFS2/1611]

Catalogue Number: GTX34479-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide\|0.05% Sodium azide
Molecular Weight:	29
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	CD27 , CD27 molecule , S152 , S152. LPFS2 , T14 , TNFRSF7 , Tp55
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	LPFS2/1611
Isotype:	IgG1
Immunogen:	Recombinant full-length human CD27 protein
Application:	ELISA, FC, ICC, IF, IHC-P, PA

Overview
Datasheets

Description

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Additional Text

Uniprot ID

P26842

Gene Name

CD27

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Gene ID

939

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

ICC/IF: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. FCM: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX34479 Datasheet

Price

£504.00

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Quantity
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