CD74 antibody [LN-2]

Catalogue Number: GTX34551-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:34
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD74 , CD74 molecule , DHLAG , HLADG , II , IaGAMMA
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: LN-2
Isotype: IgG1
Immunogen: SU-DHL-4 lymphoma cells
Application: FC, ICC, IF, IHC-P, WB, FA

Description

Description: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Additional Text

Gene ID

972

Gene Name

CD74

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Uniprot ID

P04233

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

34

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

ICC/IF: 1-4µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. FCM: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.