Estrogen Receptor alpha antibody [ER506]

Catalogue Number: GTX34710-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide\|0.05% Sodium azide
Molecular Weight:	66
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	ER , ESR , ESR1 , ESRA , ESTRR , Era , NR3A1 , estrogen receptor 1 , ER alpha , Estrogen Receptor alpha
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	ER506
Isotype:	IgG1
Immunogen:	Recombinant fragment (around aa 2-185) of human Estrogen Receptor alpha protein (exact sequence is proprietary)
Application:	FC, IHC-P, WB, PA

Overview
Datasheets

Description

Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]

Additional Text

Gene ID

2099

Gene Name

ESR1

Uniprot ID

P03372

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Molecular Weight

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1-2µg/ml. FCM: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX34710 Datasheet

Price

£504.00

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Quantity
Unit Size

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