Filaggrin antibody [FLG/1561]

Catalogue Number: GTX34731-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:435
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:ATOD2 , FLG , filaggrin , Filaggrin
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: FLG/1561
Isotype: IgG1
Immunogen: Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
Application: IHC-P, PA

Description

Description: The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009]

Additional Text

Gene Name

Flg

Purification

Protein A/G Purified

Gene ID

2312

Concentration

0.2 mg/ml

Uniprot ID

P20930

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

IHC-P: 1-2µg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.