Glypican-3 antibody [rGPC3/863]

Catalogue Number: GTX34764-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:66
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:DGSX , GPC3 , GTR22 , MXR7 , OCI5 , SDYS , SGB , SGBS , SGBS1 , glypican 3 , Glypican 3
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: rGPC3/863
Isotype: IgG1
Immunogen: Recombinant full-length human GPC3 protein
Application: FC, ICC, IF, IHC-P, PA

Description

Description: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Additional Text

Gene Name

GPC3

Gene ID

2719

Uniprot ID

P51654

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

ICC/IF: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. FCM: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.