ICAM3 antibody [186-2G9]

Catalogue Number: GTX34789-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:60
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD50 , CDW50 , ICAM3 , ICAMR , intercellular adhesion molecule 3
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 186-2G9
Isotype: IgG2b
Immunogen: Stimulated human leukocytes
Application: ICC, IF, IHC-P, NT, Inh

Description

Description: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

Additional Text

Gene ID

3385

Gene Name

ICAM3

Uniprot ID

P32942

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

ICC/IF: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.