p63 antibody [TP63/1786]

Catalogue Number: GTX34944-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:77
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:AIS , B(p51A) , B(p51B) , EEC3 , KET , LMS , NBP , OFC8 , RHS , SHFM4 , TP53CP , TP53L , TP63 , TP73L , p40 , p51 , p53CP , p63 , p73H , p73L , tumor protein p63
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: TP63/1786
Isotype: IgG2b
Immunogen: Recombinant fragment (around aa 3-106) of human p63 protein (exact sequence is proprietary)
Application: ELISA, WB, PA

Description

Description: This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]

Additional Text

Gene Name

TP63

Gene ID

8626

Uniprot ID

Q9H3D4

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Molecular Weight

77

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1-2µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.