SOX2 antibody [SOX2/1791]

Catalogue Number: GTX35086-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:34
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:ANOP3 , MCOPS3 , SOX2 , SRYbox 2 , SRY-box transcription factor 2
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: SOX2/1791
Isotype: IgG2b
Immunogen: Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
Application: ELISA, IHC-P, WB, PA

Description

Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

SOX2

Purification

Protein A/G Purified

Gene ID

6657

Concentration

0.2 mg/ml

Uniprot ID

P48431

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

34

Application Notes

WB: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 min at RT. ELISA: 2-4µg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.