SPTBN2 antibody [SPTBN2/1584]
Catalogue Number: GTX35091-GTX
GTX35091 Image
GTX35091 Image
GTX35091 Image
GTX35091 Image
GTX35091 Image
GTX35091 Image
GTX35091 Image
GTX35091 Image
GTX35091 Image
FACS analysis of HeLa cells using GTX35091 SPTBN2 antibody [SPTBN2/1584]. Blue : Primary antibody Red : Isotype control
GTX35091 Image
ICC/IF analysis of MeOH-fixed HeLa cells using GTX35091 SPTBN2 antibody [SPTBN2/1584]. Green : Primary antibody Red : nucleus
GTX35091 Image
IHC-P analysis of mouse kidney tissue using GTX35091 SPTBN2 antibody [SPTBN2/1584].
GTX35091 Image
IHC-P analysis of rat pancreas tissue using GTX35091 SPTBN2 antibody [SPTBN2/1584].
GTX35091 Image
IHC-P analysis of human pancreas tissue using GTX35091 SPTBN2 antibody [SPTBN2/1584].
GTX35091 Image
GTX35091 Image
WB analysis of HeLa cell lysate using GTX35091 SPTBN2 antibody [SPTBN2/1584].
GTX35091 Image
WB analysis of PANC-1 cell lysate using GTX35091 SPTBN2 antibody [SPTBN2/1584].
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 271 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | GTRAP41 , SCA5 , SCAR14 , SPTBN2 , spectrin beta, nonerythrocytic 2 , Spectrin Beta III , spectrin β III , spectrin beta, non-erythrocytic 2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | SPTBN2/1584 |
| Isotype: | IgG1 |
| Immunogen: | Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary) |
| Application: | FC, ICC, IF, IHC-P, WB, PA |
Description
Description: Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
Additional Text
Gene Name
SPTBN2
Purification
Protein A/G Purified
Concentration
0.2 mg/ml
Gene ID
6712
Molecular Weight
271
Uniprot ID
O15020
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 1-2µg/ml. ICC/IF: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. FCM: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX35091 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations