Thrombomodulin antibody [THBD/1591]

Catalogue Number: GTX35108-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:60
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:AHUS6 , BDCA3 , CD141 , THBD , THPH12 , THRM , TM , thrombomodulin
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: THBD/1591
Isotype: IgG2b
Immunogen: Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein (exact sequence is proprietary)
Application: ELISA, IHC-P, WB, PA

Description

Description: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

7056

Gene Name

THBD

Uniprot ID

P07204

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Molecular Weight

60

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. ELISA: 2-4µg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.