TRC8 antibody, C-term

Catalogue Number: GTX38010-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:76
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:ring finger protein 139 , HRCA1 , RCA1 , TRC8
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Goat
Clone:
Isotype: IgG
Immunogen: Peptide with sequence C-HTGAAAEEFNDDT, from the C Terminus of the protein sequence according to NP_009149.2.
Application: IHC-P, WB

Description

Description: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]

Additional Text

Concentration

0.5 mg/ml

Uniprot ID

Q8WU17

Gene ID

11236

Molecular Weight

76

Purification

Ammonium Sulfate Precipitated; Affinity Purified

Gene Name

RNF139

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.