TNF alpha antibody [F6C5]

Catalogue Number: GTX38737-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:26
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:tumor necrosis factor , DIF , TNF-alpha , TNFA , TNFSF2 , TNLG1F
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 500 ug
Host name: Mouse
Clone: F6C5
Isotype: IgG1
Immunogen: Human recombinant tumor necrosis factor of alpha type.
Application: IA, IHC-Fr, NT, Inh

Description

Description: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

TNF

Gene ID

7124

Uniprot ID

P01375

Concentration

8.2 mg/ml

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.