proBNP antibody [15C4], N-term (Biotin)

Catalogue Number: GTX39520-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:15
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:natriuretic peptide B , BNP
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 200 ug
Host name: Mouse
Clone: 15C4
Isotype: IgG2b
Immunogen: Synthetic N-terminal proBNP peptide, corresponding to amino acids 61-76 coupled to a carrier protein.
Application: ELISA, WB, LF

Description

Description: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]

Additional Text

Gene Name

NPPB

Gene ID

4879

Uniprot ID

P16860

Concentration

1.2 mg/mL

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

15

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.