Myelin basic protein antibody [V/h5]

Catalogue Number: GTX39736-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	33
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	Myelin basic protein
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Mouse
Clone:	V/h5
Isotype:	IgG1
Immunogen:	N-terminal fragment of human MBP (residues 1-118) produced by BNPS-skatole cleavage of pure human MBP, injected coupled to BSA using carbodiimide.
Application:	ELISA, RIA

Overview
Datasheets

Description

Description: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

MBP

Gene ID

4155

Purification

Protein A purified

Uniprot ID

P02686

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX39736 Datasheet

Price

£499.00

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