Apolipoprotein A1 antibody [1402]

Catalogue Number: GTX40411-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:apolipoprotein A1 , apo(a)
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 1402
Isotype: IgG1
Immunogen: Purified human plasma Apo A-I
Application: RIA, EIA

Description

Description: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]

Additional Text

Gene Name

APOA1

Uniprot ID

P02647

Gene ID

335

Concentration

6.45 mg/ml

Purification

Ion Exchange

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

31