Factor VII antibody [RFF-VII/2]

Catalogue Number: GTX41196-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	52
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	coagulation factor VII , SPCA
Shipping Condition:	Blue Ice
Unit(s):	500 ug
Host name:	Mouse
Clone:	RFF-VII/2
Isotype:	IgG1
Immunogen:	Purified Factor VII.
Application:	ELISA, WB, RIA

Overview
Datasheets

Description

Description: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]

Additional Text

Gene Name

Uniprot ID

P08709

Gene ID

2155

Purification

Protein G purified

Molecular Weight

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX41196 Datasheet

Price

£610.00

-

Quantity
Unit Size

Find out about delivery