Properdin antibody [10-18]

Catalogue Number: GTX41202-GTX

Manufacturer:	GeneTex
Preservative:	0.1% Sodium azide
Molecular Weight:	51
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	complement factor properdin , BFD , PFC , PFD , PROPERDIN
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	10-18
Isotype:	IgG1
Immunogen:	Native purified factor P from human serum.
Application:	ELISA, IHC-Fr, NT, Inh

Overview
Datasheets

Description

Description: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]

Additional Text

Uniprot ID

P27918

Gene ID

5199

Gene Name

CFP

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX41202 Datasheet

Price

£620.00

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