Dectin-1 antibody [GE2] (Low endotoxin, azide free)

Catalogue Number: GTX41459-GTX

Manufacturer:GeneTex
Preservative:azide free|no preservative|No preservative
Molecular Weight:28
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:C-type lectin domain containing 7A , BGR , CANDF4 , CD369 , CLECSF12 , DECTIN1 , SCARE2
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: GE2
Isotype: IgG1
Immunogen: NIH3T3 cells expressing full length Dectin-1
Application: FC, FA

Description

Description: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CLEC7A

Uniprot ID

Q9BXN2

Gene ID

64581

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

FCM: Neat-1/25. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.