Interferon gamma antibody [4S.B3] (Biotin)

Catalogue Number: GTX41538-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 4S.B3
Isotype: IgG1
Immunogen: Partially purified, native human Interferon gamma
Application: ELISA, ELISPOT, FC

Description

Description: Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.

Additional Text

Concentration

0.5 mg/ml

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

ELISA: Use at a concentration of 0.5 - 2 µg/ml. ELISPOT: Use at a concentration of 1 - 4 µg/ml. FACS: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.