Factor H antibody [OX-23]

Catalogue Number: GTX41629-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:139
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:complement factor H , AHUS1 , AMBP1 , ARMD4 , ARMS1 , CFHL3 , FH , FHL1 , HF , HF1 , HF2 , HUS
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Mouse
Clone: OX-23
Isotype: IgG1
Immunogen: Human complement factor H.
Application: ELISA, IP, WB, RIA

Description

Description: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

Additional Text

Gene Name

CFH

Uniprot ID

P08603

Gene ID

3075

Molecular Weight

139

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

ELISA: 1/50-1/200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.