CD68 antibody [ED1]

Catalogue Number: GTX41868-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:37
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD68 molecule , GP110 , LAMP4 , SCARD1
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: ED1
Isotype: IgG1
Immunogen: Rat spleen cells
Application: FC, ICC, IF, IHC-P, IP, WB, RIA, IHC-Fr

Description

Description: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CD68

Gene ID

968

Uniprot ID

P34810

Concentration

0.5 mg/ml

Molecular Weight

37

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

FCM: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.