Integrin alpha V antibody [RMV-7]

Catalogue Number: GTX41923-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:115
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:integrin alpha V , 1110004F14Rik , 2610028E01Rik , CD51 , D430040G12Rik
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rat
Clone: RMV-7
Isotype: IgG1
Immunogen: Cultured LAK cells from Balb/c mice.
Application: FC, IP, IHC-Fr

Description

Description: This gene encodes a protein that is a member of the integrin superfamily. Integrins are transmembrane receptors involved cell adhesion and signaling, and they are subdivided based on the heterodimer formation of alpha and beta chains. This protein has been shown to heterodimerize with beta 1, beta 3, beta 6 and beta 8. The heterodimer of alpha v and beta 3 forms the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. In mouse, deficiency of this gene is associated with defects in vascular morphogenesis in the brain and early post-natal death. [provided by RefSeq, May 2013]

Additional Text

Gene Name

ITGAV

Purification

Protein G purified

Gene ID

16410

Uniprot ID

P43406

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

IHC-Fr: 1/25-1/100. FCM: 1/10-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.