Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free)

Catalogue Number: GTX41962-GTX

Manufacturer:	GeneTex
Preservative:	azide free\|no preservative\|No preservative
Molecular Weight:	115
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	integrin subunit alpha 4 , CD49D , IA4
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	44H6
Isotype:	IgG1
Immunogen:	HOON pre-B leukaemia cell line.
Application:	FC, IHC-Fr, FA

Overview
Datasheets

Description

Description: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Additional Text

Gene Name

ITGA4

Gene ID

3676

Uniprot ID

P13612

Purification

Ion Exchange

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

FCM: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX41962 Datasheet

Price

£499.00

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Quantity
Unit Size

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