TLR2 antibody [11G7] (Low endotoxin, azide free)
Catalogue Number: GTX42126-GTX
| Manufacturer: | GeneTex |
| Preservative: | azide free|no preservative|No preservative |
| Molecular Weight: | 90 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | toll like receptor 2 , CD282 , TIL4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 11G7 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | FC, IP, FA |
Description
Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Additional Text
Gene Name
TLR2
Gene ID
7097
Purification
Protein G purified
Uniprot ID
O60603
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
FCM: 1/100-1/200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX42126 Datasheet
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