PD1 antibody [RMP1-30]

Catalogue Number: GTX42140-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	32
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	programmed cell death 1 , Ly101 , PD-1 , Pdc1
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	100 ug
Host name:	Rat
Clone:	RMP1-30
Isotype:	IgG2b
Immunogen:	PD-1 transferred BHK cells.
Application:	FC, FA

Overview
Datasheets

Additional Text

Gene Name

PDCD1

Concentration

0.5 mg/ml

Purification

Affinity Purified

Gene ID

18566

Uniprot ID

Q02242

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The RMP1-30 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein member of the Ig superfamily of molecules. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.

GTX42140 Datasheet

GTX42140 Reference

Price

£332.00

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