IGF1R alpha antibody [AMY10-105.8 (1H7)] (Low endotoxin, azide free)

Catalogue Number: GTX42246-GTX

Manufacturer:	GeneTex
Preservative:	azide free\|no preservative\|No preservative
Molecular Weight:	155
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	insulin like growth factor 1 receptor , CD221 , IGFIR , IGFR , JTK13
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	AMY10-105.8 (1H7)
Isotype:	IgG1
Immunogen:	Purified human placental IGF-I receptor.
Application:	FC, IHC-P, WB, NT, Inh

Overview
Datasheets

Description

Description: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Additional Text

Gene Name

IGF1R

Gene ID

3480

Uniprot ID

P08069

Purification

Protein G purified

Molecular Weight

155

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

IHC-P: 1/10-1/40. FCM: 1/10. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX42246 Datasheet

Price

£349.00

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