Hemoglobin (A0, A2, S, methemoglobin) antibody [B525M]

Catalogue Number: GTX42298-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:16
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:hemoglobin subunit gamma 2 , HBG-T1 , TNCY
Shipping Condition:Blue Ice
Unit(s): 500 ug
Host name: Mouse
Clone: B525M
Isotype: IgG1
Immunogen: Human Hemoglobin
Application: ELISA, LF

Description

Description: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

Additional Text

UniProt ID

P69892

Gene Name

HBG2

Concentration

8.45 mg/ml

Gene ID

3048

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.