Fas Ligand antibody [10F2] (Low endotoxin, azide free)

Catalogue Number: GTX42345-GTX

Manufacturer:GeneTex
Preservative:azide free|no preservative|No preservative
Molecular Weight:31
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Fas ligand , ALPS1B , APT1LG1 , APTL , CD178 , CD95-L , CD95L , FASL , TNFSF6 , TNLG1A
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 10F2
Isotype: IgG1
Immunogen:
Application: ELISA, FC, IP, NT, Inh, InVivoA

Description

Description: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]

Additional Text

Gene Name

FASLG

Uniprot ID

P48023

Gene ID

356

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

FCM: 1/25-1/50. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.