CD11c antibody [CBR-p150/4G1] (Azide free)

Catalogue Number: GTX42471-GTX

Manufacturer:GeneTex
Preservative:Azide free|no preservative|No preservative
Molecular Weight:128
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:integrin subunit alpha X , CD11C , SLEB6
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: CBR-p150/4G1
Isotype: IgG2a
Immunogen: Recombinant human CD11c.
Application: FC, IHC-Fr, NT, Inh

Description

Description: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Additional Text

Gene Name

ITGAX

Gene ID

3687

Purification

Protein A purified

Uniprot ID

P20702

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

IHC-Fr: 5-10µg/ml. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.